Fusarium blight caused by Fusarium oxysporum f. sp. vasinfectum is a disease that causes the most damage in cotton growing. However, the use of pesticides, especially fungicides as a solution to the pathogen, has proven to be not only ineffective but also leads to problems of toxicity, environmental pollution, health and even biodiversity. The objective of this work was to study the variability of the production of phenolic compounds involved in the natural defense system of the cotton plant. Thus, the application of the MeJA and OSF 11 elicitors (10%) on the cotton plants followed by inoculation with FOV allowed the de novo synthesis of phenolic compounds in addition to the preexisting compounds. Moreover, the accumulation of phenolic compounds was amplified following the application of these two elicitors followed by inoculation with FOV. The cotton plants were therefore equipped with
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