the Total SGRQ score (r= 0.73) and Symptoms (r= 0.62); Activity (r= 0.55), Impact (r= 0.72) subscales; the modified MRC Dyspnoea scale (r= 0.54), FACIT-F (r= -0.66); HADS Anxiety (r= 0.53) and Depression (r= 0.54). The MEMSI also demonstrated good overall fit to the Rasch model (Chi-squared 26.6; df 20; p= 0.26) and distribution of item scores. ConClusions: The final MEMSI contains 10-item and is a reliable, valid, unidimensional self-reported outcome measure of early morning symptoms for people with COPD. It is quick and simple making it suitable for use in research and practice. Further work is underway to determine the minimal clinical important difference.