No abstract

Energy metabolism regulator Amber-anti-tox had a systemic effect under experimental conditions of vibration-induced dysregulation. Whole-body vibration was accompanied by nonlinear changes in energy metabolism in the heart, liver, kidneys, and lymphocytes and impairment of intra-systemic inter-organ relationships between mitochondria. Amber-anti-tox prevented vibration-induced de-energization of mitochondria and contributed to the preservation of multidimensional relationships of energy metabolism in vital internal organs.

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Multivariate factor analysis of the data on liver bioenergetics of mountain and forest voles has been performed. The specific features of tissue energy metabolism are best differentiated in the space of characters pertaining to the succinic acid oxidation system. The role of the dominant oxidation substrate in the structure of energy supply for the adaptation of tissue to a set of environmental factors in specialized and widespread species is discussed.