Primary thyroid non-Hodgkin's lymphoma is a rare entity. It is defined as a lymphoma occurring in the thyroid gland with or without the involvement of regional lymph nodes. Diffuse large B-cell lymphoma is the predominant subtype, followed by the extranodal marginal zone B-cell lymphoma of MALT, mantle cell lymphoma, SLL, and follicular lymphoma. Hashimoto's thyroiditis is considering as a causal factor. Diffuse large B-cell lymphoma and mantle cell lymphoma are known by an aggressive course while MALT lymphoma and small lymphocytic lymphoma (SLL) are characterized by an indolent clinical course. The most common clinical presentation is an enlarging painless neck mass, growing rapidly and causing an obstruction of the upper airway. Differential diagnosis is an anaplastic carcinoma, squamous cell carcinoma, metastasis of unknown primary and thyroiditis. The sensitivity and the specificity of the FNAC can be increased if consolidated by the use of the flow cytometry, the immunohistochemistry (IHC) and PCR.Three modalities of treatment could be proposed: surgery, radiotherapy, and chemotherapy-dependent on the histologic subtype.
Desmoid tumor is a proliferation of a mesenchymal, fibroblastic or myofibroblastic tissue. It is a non-capsulated tumor. Despite its benign nature, desmoids tumor have an aggressive behavior.Its localization in the parotid gland has rarely been reported in the literature.The particularity of this location in the head and neck is the proximity of Vascularnervous structures, the facial nerve in the parotid location and the consequence, if affected, on the facial motility especially that this tumor often occurs in young people. The clinical presentation is often about a slow-growing mass characterized by being: painless, ill-defined, firm, non-inflammatory, deeply located, and fixed to the underlying structures. Treatments strategies, always made by a multidisciplinary committee, are based on the natural biological behavior of this deep fibromatosis which is unpredictable and variable. Surgery could be undergone every time it is radical. Radiotherapy could also be played. However, the most relevant point is that actually, most authors highlighted the conservative approach by the "wait and see" policy for primary as well as for recurrence of the disease after surgical resection or radiotherapy.
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