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LYMPHOCYTE removal through external thoracic duct fistulae causes persistent lymphocytopenia and atrophy of peripheral lymphoid tissue in the experimental animal.y,10 The primary immune response to antigenic stimulation is similarly diminished.14 Clinically, fluid retention in hepatic cirrhosis with ascites and congestive heart failure has been benefited by chronic depletion of lymph.5'7Stimulated by the work of Dumont,6 Bloomstrand,2 and Artz,I we have employed thoracic duct drainage as an adjunct to immunosuppression in 14 patients undergoing renal transplantation at the Peter

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