The long-term competitiveness of national economies directly depends on their innovativeness. The paper analyzes a set of indicators measuring the impact of science and technology on national competitiveness. Among the indicators analyzed are the number and type of enterprises engaged in R&D, the volume of budget funding of science, and the number of developed and used advanced production technologies. Emphasizing the differences between the sustainable state and sustainable development, the authors discuss the need and practicality of supporting innovations to ensure the sustainable development of the Russian economy and the integration of goals of innovation and sustainable development. The reasoning of conclusions and proposals is based on official statistics and understanding of most critical aspects in scientific and technological development.