Introduction: Hypothyroidism is widely prevalent in pregnant women and the rate of detection, especially on a developing country like India, has not kept pace with the magnitude of the problem (1). Since hypothyroidism is easily treated, timely detection and treatment of the disorder could reduce the burden of adverse fetal and maternal outcomes, which are very commonly encountered (1). Congenital hypothyroidism can be caused due to thyroid dysgenesis, disorders of thyroid hormone synthesis, iodine deficiency or excess as well as trans-placental transfer of maternal antibodies or medications. (1). Congenital hypothyroidism is a preventable cause of intellectual disability. Hence it is important to monitor neonates born to mothers with hypothyroidism Hypothyroidism is widely prevalent in pregnant women and the rate of detection, especially in a developing country like India needs to be treated and detected early (3). Aims and Objectives: To detect and prevent congenital hypothyroidism in neonates born to mothers with hypothyroidism and their neonatal outcomes. To screen the neonates for congenital hypothyroidism. Methods: All the pregnant women visiting the antenatal OPD at KIMS Narketpally were screened for hypothyroidism during the first antenatal visit. The present study was conducted on 27 women with the diagnosis of hypothyroidism in pregnancy who came to the antenatal OPD and who were delivered at KIMS Narketpally. The neonates born to these mothers were screened for hypothyroidism on day 5 of life in order to detect congenital hypothyroidism in the neonate. Results:In the present study all the 27 mothers diagnosed with Hypothyroidism in pregnancy were taken. The TSH value of most of the mothers with Hypothyroidism was between 3 to 4.9 and most of the mothers were controlled on treatment with Tab.Thyronorm 25mcg.The neonates born to these mothers were screened on Day 5 of life to detect congenital Hypothyroidism. In the present study it showed that none of the neonates born to these Hypothyroid mothers had congenital hypothyroidism because of early diagnosis and Treatment of the mothers in the antenatal period. Conclusion:In the present study it was observed that all the neonates born to the mothers with Hypothyroidism had normal TSH values and none of the neonates had congenital hypothyroidism dues to early diagnosis and treatment.