A mycoplasma strain, isolated from natural synovitis of guinea-fowl, was identified as Mycoplasma synoviae. In experimental infection this agent showed clear pathogenicity for guinea-fowl, and to a lesser degree for chickens. In guinea-fowl the strain was more likely to result in synovitis and amyloidosis when inoculated by the intravenous route and to produce sinusitis after intrasinusal inoculation.
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