Purpose: physiological substantiation of the physical activity selection based on the differences in the functional state of schoolchildren with different types of cardiovascular system autonomic regulation.Methods: 60 schoolchildren, 12 years old, were examined. The experimental group consisted of schoolchildren who were engaged in physical exercises for 6 months according to the developed individual typological program. Students in the control group followed the school programm. The assessment of the functional state was carried out by the method of “Express assessment of the physical health of schoolchildren” and the method of diagnosing indicators of heart rate variability.Results: at the beginning of the survey, the indicators in the experimental group and the control group were determined by the characteristics of 4 types of autonomic regulation: I, II, III, IV. Of these, I, II corresponded to the predominance of sympathetic-tonic destabilizing influences on the cardiovascular system, in IV parasympathetic influences prevailed, manifested in the asthenia of the functional state of students. Whereas type III refers to the physiological norm and manifested itself in the form of a balance of regulatory influences of the parts of the autonomic nervous system.Conclusions: at the control examination, the indicators of adaptation and health improved in all types of schoolchildren, while in the control group there was no positive dynamics of indicators of adaptation and health. This testifies to the effectiveness of individually typologically oriented classes at a physical education lesson as having a health-improving effect on schoolchildren.

The paper analyzes the theoretical foundations of social adaptation of children with autism spectrum disorders. Attention is focused on the widespread prevalence of autism not only in the Russian Federation, but also abroad, which makes the problem of social adaptation of children with autism spectrum disorders relevant today. The paper presents the data of a sociological survey on the problems of social adaptation and the organization of the educational process for children with autism. The paper reveals statistical indicators on the problems of autism in world practice and in the Russian Federation, focuses on disorders of the mental and psychological state, shows a deficit of emotional reactions, disturbances in the communicative sphere, and the lack of independence of children with autism. It is also noted that these children are immersed only in their own problems, not noticing the world around them.

The purpose was to study the opinion on the advisability of using biologically active additives for the prevention and treatment of diseases among the students of the Voronezh State Medical University named after N. N. Burdenko. To achieve the goal of the study, a questionnaire containing 13 questions of various types was created for student testing. The study participants were 2–4‑year students of medical, pediatric and dental faculties (54 students in total, average age — 20 years). The survey was conducted using online technologies.By the time of the survey, all respondents were in the process of studying or had completed the course of biochemistry, 38 % had completed the course of pharmacology.

The authors show that the dynamics of the birth rate of the BSSR population is characterized by a gradual drop from the mid-1920s to mid-1930s to a minimum in 1933–1934, with fluctuations within the limits of the trend; the death rate is generally stable with the similar fluctuation within the trend. The dynamics of the birth and death rates in 1933–1934 are shown as population waves with a maximum (fall) in seasonal birth (death) rate is compensated by its seasonal increase (drop). The death rate increase and negative natural growth of the population in the urban environment are localized and insignificant. For the majority of the BSSR, its demographic indicators are not pointing to a demographic crisis: either a high birth rate with a relatively low death rate was prevailing, or a drop in the birth rate didn’t result in the abrupt natural growth decrease, which remained positive. A lower birth rate and a higher death rate can be attributed to different causes other than famine. The only two regions with a high death rate and a negative natural growth of population were Narovlyansk and Elsk — two districts on the border with Ukraine. This is the exact area of the BSSR affected by the famine as confirmed by the official papers and the demographic indicators. The loss of the BSSR population due to the drop in birth rate in 1932–1934 is approximately 64,000 people; the direct decrease due to the death rate is 4,100 people; both are within the limits of the trend fluctuations and cannot be considered as a demographic crisis. In general, the indicators in the BSSR do not point to the demographic catastrophe.

Type V hyperlipoproteinemia or multifactorial chylomicronemia syndrome is a rare lipid disorder triggered mainly by uncontrolled diabetes, obesity, poor diet, or particular medications. It is associated with an increased risk of acute pancreatitis and accelerated coronary artery disease which may manifest in younger age groups. We present a case of a 42-year-old male who presented to the emergency department (ED) complaining of a non-healing hand injury. Upon laboratory workup, the patient was found to have an elevated total cholesterol (TC) of 1129 mg/dL, very low levels of high-density lipoprotein (HDL) and triglycerides (TG) > 4000 mg/dL with an inability to calculate low-density lipoprotein (LDL). Lipoprotein electrophoresis revealed an actual TG level of > 7000 mg/dL, increased chylomicrons, normal B and pre-Blipoproteins, and increased L-lipoproteins with an elevated Apolipoprotein B. Despite these derangements, the patient did not exhibit any abdominal complaints, demonstrating a normal lipase level. The physical exam was indicative of bilateral arcus senilis and obesity. Insulin drip was initiated along with intravenous (IV) hydration and it required 12 days to bring triglycerides down to less than 1000 mg/dL. The total cholesterol was also seen to be down trending to around 500 mg/dL and the HDL improved to 22 mg/dL. We present this case as a unique presentation of asymptomatic chylomicronemia resistant to insulin treatment with an elevated ApoB but with no evidence of pancreatitis or coronary artery disease.