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This communication gives the results of a further chemical study of the flavonoids of Lepidium perfoliatum L. (clasping pepperweed) [1]. By chromatography on Kapron using isopropanol and isobutanol eluents we isolated an individual flavonoid glycoside, which we have called "lepidoside." Lepidoside consists of small yellowish-green acieular crystals soluble in water and alcohols with mp 259-261 o C (from ethanol); [~]D-65° (methanol); Rf 0.68 (15% acetic acid), 0.79 (50% formic acid); kma x in ethanol, mp: 350,

The ethereal solution was separated into acidic, phenolic, and lactone fractions. The acidic fraction was chromatographe d on KSKsilica gel. On elntion with ether, acicular crystals with mp 201-202 ° C deposited which, on the basis of their IR spectrum, P,f value, and a mixed melting point were identified as the coumarin scopoletin. Then the unsaponifiable neutral fraction was chromatographed on alumina. From a methanolic eluate we isolated a substance with the composition C~sHs00, mp 139-140 ° C (from acetone), which gave the Liebermann-Burehard reaction for sterols. By comparing the IR spectra and ROt values and by means of a mixed melting point test the substance was identified as g-sitosterol. Seopoletin and 13-sitosterol have not previously been found in Artemisia dracunculus.

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