The papir results of research of biochemical parameters in whey of blood of albino rats in conditions of influence of an external irradiation in a doze 0,5 and 1 Gy are submitted. The analysis of dependence of various biochemical parameters from a doze and time of an external irradiation is lead.

Objective. To study the level of endogenous respiration of the small intestine mucosa of experimental animals after exposure to external irradiation at a dose of 0.5 and 1.0 Gy.Materials and methods. The study was conducted on white male outbred rats weighing 180-200 g. The animals were irradiated once in the “IGUR-1” unit, 137Cs source, dose rate 0.92 Gy/min. The parameters of tissue respiration were studied by polarographic method using Record-4 device (RF) in a 2 ml cell with a closed platinum Clark electrode at 25°C.Results. It was shown that changes in respiratory activity over time are non-monotonous. This confirms the high sensitivity of the small intestine to radiation exposure.Conclusion. The level of endogenous respiration of the small intestine mucosa can be one of the criteria for assessing the energy status of the tissue after irradiation.

Objective: to study the indicators of tissue respiration and oxidative phosphorylation of the rings of the mucous membrane of the duodenum intact in white rats. Material and methods. We used white male rats with body mass of 180-230 g. The parameters of tissue respiration and oxidative phosphorylation were studied by the polarographic method on the device «Record 4». Results. The work gives the characteristic of the key parametres of tissue respiration and oxidative phosphorylation of the mucous membrane of the small intestine of intact white rats. It shows high respiratory activity both on endogenous, and exogenous substrates, which is caused by the fact that the small intestine perform a great number of energy-dependent metabolic functions. Conclusion. Saturated and unsaturated fatty acids make a great contribution to the energy properties of the small intestine. The intensity of tissue respiration and oxidative phosphorylation of the mucous membrane of the small intestine is consistent with other aerobic tissues.