Cholesterol and its esters with aliphatic acids were studies as agents increasing the transdermal penetration of phenazepam when given transdermally in mice. Drug penetration was measured in terms of its pharmacological action (anticonvulsive effect on intravenous administration of 1% corasole). These studies showed that of the compounds studied, cholesteryl pelargonate had the greatest enhancing effect.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.