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In the Russian literature, there are only a few works that summarize their own experience in the treatment of recurrent corneal erosion (RCE) in a limited group of patients, which actualizes further research in this direction.Objective: to develop and evaluate the clinical effectiveness of an integrated approach to the management of patients with RCE.Patients and methods. 69 patients (69 eyes) with RCE and a disease duration of at least two years, who were divided into 3 groups according to the frequency of relapses: group 1 (12 people) — episodes of RCE no more than 2–4 times a year; Group 2 (19 people) — RCE episodes no more than once a month; Group 3 (38 people) — RCE episodes more than 2 times a month. All patients were cured by pharmacological support, if conservative therapy was ineffective (1 relapse during treatment within 1 month), phototherapeutic keratectomy (PTK) was performed with the application of a bandage contact lens and the appointment of pathogenetically-oriented treatment for up to 1 year. The average follow-up period was 28.6 ± 6.1 months.Results and discussion. In group 1, during the entire period of observation, RCE was compensated by the therapy, in the other groups, the effectiveness was lower, which in 41 (59.4 %) cases required the implementation of PTK. There were no relapses of corneal erosion after PTK with subsequent pathogenetically-oriented therapy, including heparin-containing medications in instillation (CHYLOPARIN-KOMOD®) and ointment forms (PARIN-POS®) for 1 year.Conclusion. The high effectiveness of PTK with subsequent pathogenetically-oriented pharmacological support may be the basis for a broader recommendation of this method in patients with RCE and a relapse rate of more than 1 time a month.

Purpose. To evaluate the clinical and functional results of the technique of ultraviolet crosslinking on the thin cornea using a customized soft contact lens without an ultraviolet filter in a patient with secondary corneal ectasia. Material and methods. Under observation was patient S., 32 years old, diagnosed with secondary keratoectasia of the left eye after LASIK surgery, performed in 2008 for moderate myopia. To stabilize the keratectatic process, complicated by the presence of a thin cornea with a thickness of less than 400 microns, an operation was performed: ultraviolet crosslinking of corneal collagen using a customized protective lens without an ultraviolet filter. Results. There were no complications during and after the operation. According to keratorefractometry and keratotopography, there was no progression of the disease after surgery, and no loss of endothelial cells was detected. Conclusion. Thus, conducting ultraviolet crosslinking of corneal collagen using a protective customized lens without an ultraviolet filter is a promising technique that allows you to achieve stabilization of the keratectatic process. Key words: corneal ectasia, thin cornea, UV crosslinking, customized lens.