Abstract:Exercise is known to increase free fatty acid and glucose metabolism. In consideration of such physiological effects of leptin such as reducing food intake and increasing energy consumption, many researchers have studied the relation between leptin and exercise. Despite the inconsistency between results, it is generally accepted that physical activity causes changes in leptin secretion. The present study aims to determine the changes that occur in plasma leptin levels of the rats subjected to acute swimming exercise, immediately after exercise, and in the 24th and 48th hours following exercise.