In the present study, in vitro bioassay screening of total methanolic extracts of two Juniperus species (Juniperus horizontalis Moench. and Juniperus communis L.) cultivated in Egypt for schistosomicidal and molluscicidal activities was carried out. Schistosoma mansoni Sambon worms and Biomphalaria alexandrina (Ehrenberg) snails were used. The screening results showed that both tested extracts had almost similar schistosomicidal activity (LC50 ≈ 91 µg/ml, in 3 days) while J. communis extract possess more potent molluscicidal activity than J. horizontalis (LC 50 = 22.9 and 38.9 ppm, after one day, respectively). Analysis of the chemical composition of the essential oils obtained by hydro-distillation of the aerial parts of the two Junipers species was done by GC/MS. Sixty seven (94.32%) components were identified in J. communis oil with homogeraniol (36.95%) being the major constituent, while sixty (95.39%) components were identified in J. horizontalis oil with the main component, bronyl acetate representing 41.17%.

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