Knowing that heavy metals are characterized by the cumulative effects on the one hand and that they are present in biological systems at very low doses, which makes their effects latent and often irreversible. It is in this perspective and in order to try to solve the problem of detoxification of this type of major contaminant, we opted for an effective solution which is detoxification by antagonism based on selective interaction. The choice is made for Cadmium which is considered a very harmful element on the one hand and its almost total presence in the entire ecosystem. The investigation protocol is based on two complementary steps which are: • Determination of the Cadmium toxicity threshold vis-àvis the selected plant Phaseolus-Vulgaris. • Study of the interaction between and Cadmium and Zinc and Cadmium Copper selected for the application And the verification of the reduction of the harmful effect by selective competition.

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