A total of 50 human blood samples with Amoebic dysentery were obtained from people between the ages of 7-66 years for a period of three months from November 2017 to January 2018 from three hospitals (Murjan Medical City hospital, AL-HillaTeachinghospital, and AL-Mahaweel hospital) in Babylon province, Iraq. While the other 30 samples of healthy people (7-63 years) were seen as a control group, were collected from donors from Babylon Governorate to assess the state of oxidative stress in people with acute Entamoebahistolytica infections.The state of oxidative stress was determined by valuing the levels of serum malondialdehyde (MDA) and serum glutathione (GSH) as an indicator of lipid peroxidation and antioxidant status respectively. Serum MDA and serum GSH levels for Group of sick people were 18.125± 4.56μmol/L and 194.434±23μmol/L respectively, which MDA level was significantly higher than that in the control group 13.285 ± 2.87μmol/L whereas the GSH level was lower than that in the control group 559.25±55μmol/L (P<0.001). Serum MDA levels were increased significantly with increasing age (P<0.001). The acute infection of the amoeba parasite under study was directly associated with a sharp increase in free radicals by increasing MDA levels and lower GSH levels in people with parasite compared to uninfected persons, confirming the important role of parasites in inducing oxidative stress.
Background: some microbial infections can be passed to the fetus before or during birth and damage the fetus or cause a miscarriage, like infection with ToRCH agents and salmonella enterica. The current study aims to investigate the extent of the involvement of salmonella enteria serovars, proteus spp. and Brucella spp. in recurrent miscarriage in women during first trimester. Material and method: The 50 blood samples were collected from women age rage (19-39), who had repeated miscarriages during the first trimester during periods extended from October 2021 to February 2022,. The study control includes the 20 fertile women with no miscarried history. Two tests were conducted which are ToRCH IgM and febril antigen slid test for identification infectious agents associated with pregnancy loss. Results: The present results showed that the most frequent recurrent miscarriage (RM) was in the age group 35-39 years at a percentage 34%, while the lowest abortion rate was 18% at the age group of 25-29 years.
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