The aim of this work was to determine the effect of dietary vitamin E intake on lipid peroxidation (LPO) by measuring thiobarbituric acid reactive substances (TBARS), vitamin E and reduced glutathione (GSH) levels, and glutathione peroxidase (GSH-Px: EC 1.11.1.9) activity in plasma, red blood cells (RBC), livers, and kidneys of rabbits dosed with cadmium (Cd). Six-month-old clinically healthy New Zealand White rabbits (8 in each group) were given tap water only, containing 1 g CdCl2/L, or tap water with CdCl2 plus vitamin E (100 mg dl-alpha-tocopheryl acetate in 0.2 mL corn oil) daily for 30 days. The vitamin E level in the plasma, liver, and kidneys was significantly higher in the control than in the Cd-only group, and TBARS levels were significantly lower. There were no statistical differences between the control and Cd-only groups GSH-Px activities and GSH levels in RBC, liver, and kidneys. Vitamin E levels in plasma, liver, and kidneys and GSH-Px activity in RBC were higher in the vitamin E group than in both control and Cd-only groups. However, the TBARS levels of RBC, liver, and kidneys in vitamin E administered group were decreased. Therefore, the present study demonstrates the effectiveness of vitamin E in reducing oxidative stress in Cd-treated rabbits and suggests that reductions in increased TBARS due to Cd toxicity may be an important factor in the action of vitamin E.

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The aim of the present study was to investigate whether epidural administration of a xylazine-lidocaine combination accompanied by xylazine sedation would provide satisfactory analgesia for some surgical procedures on 10 calves admitted to the Department of Veterinary Surgery, University of Kafkas with perineal urolithiasis (n:2), rectovaginal fistula (n:1), atresia ani (n:2), omphalophlebitis (n:2), omphaloarteritis (n:1) and umbilical hernia (n:2).Following intramuscular injection of xylazine at a dose of 0.05 mg/kg for sedation, xylazine-lidocaine combination (0.2 mg/kg lidocaine + 0.02 mg/kg xylazine + 5 ml 0.9% NaCl) was administrated into the lumbosacral (L6-S1), sacrococcygeal (S5-Co1) or intercoccygeal (Co1-Co2) space. Heart rate, respiratory rate and rectal temperature were recorded prior to and during analgesia at 5, 10, 15, 30 and 60 minutes. Furthermore, depth and duration of analgesia were evaluated during surgical intervention.The study revealed that the combination of epidural xylazine-lidocaine with xylazine sedation was highly satisfactory for surgery of the lower urinary tract and the perineal region, but it was less so for surgery of the umbilical area.

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Bu çalýşmada üreme mevsimi dýşýnda bulunan Tuj ýrký koyunlarda Testosteron antikoru, β-karoten ve E vitamini uygulamalarý ile çoğul gebeliğin artýrýlmasý ve MDA (Malondialdehit) düzeylerinin azaltýlmasý amaçlanmýştýr. Testosteron antikoru kastre edilmiş Tuj ýrký bir koçtan elde edildi. Çalýşma 29 adet koyunda 3 grup halinde yapýldý. Grup I'deki koyunlara (n=10) vaginal süngerlerin uygulanmasýndan 1 hafta önce testosteron antikoru, β-karoten ve E vitamini uygulandý. Grup II'deki (n=9) koyunlara testosteron antikoru uygulandý. Grup III'deki (n=10) koyunlar ise kontrol grubunu oluşturdu. Koyunlardaki östrus oranlarý; I. Gruptaki koyunlarda %90.0, II. Gruptaki koyunlarda %88.9 ve III. Gruptaki koyunlarda %100.0 olarak belirlendi. Gebelik oranlarý ise Grup I, II ve III'de sýrasýyla %40.0, %33.3 ve %50.0 oranýnda belirlendi. Grup I ve Grup II'deki koyunlarda çoğul gebelik elde edilirken kontrol grubu koyunlarda çoğul gebelik elde edilmedi. Gebe ve gebe olmayan tüm koyunlarda vaginal sünger uygulamasýndan 28 gün sonra plazma MDA düzeylerinin arttýğý belirlendi ancak gruplar arasýnda istatistiksel olarak önemli bir fark tespit edilmedi (P>0.05). Sonuç olarak testosteron antikoru, β-karoten ve E vitamini uygulamasýnýn çoğul gebelik görülme oranýnda artýşa neden olduğu görüldü.