Abstract. In this era many, natural products are known to have potential as antioxidants, such as garlic, shallots, turmeric, ginger, nutmeg, paprika, lemongrass, and legumes. However, public interest to consume antioxidants from natural products is less. Because it has a bad taste when consumed directly. Therefore, must be processed to increase public interest in the consumption of antioxidants from natural products. One of them is made into pastilles. The purpose of this research was to determine the base formulation of pastilles as an optimal delivery model for antioxidant. The base of the pastilles was made using the molding mixture method with variations of sucrose and glucose syrup formula 1 (60%:15%); formula 2 (60%: 20%); formula 3 (60%: 25%). Based on the basic evaluation including organoleptic test, Gravimetric method of water content test, size uniformity test, weight diversity test, friability test, and dissolving time test, the optimal base is obtained in formula 1 because it satisfy all the evaluation requirements for pastilles. Abstrak. Saat ini sudah banyak bahan alam yang diketahui memiliki potensi sebagai antioksidan seperti bawang putih, bawang merah, kunyit, jahe, pala, paprika, serai, dan legkuas. Akan tetapi, minat masyarakat dalam hal konsumsi antioksidan dari bahan alam masih kurang. Karena memiliki rasa yang kurang enak apabila dikonsumsi secara langsung. Oleh karena itu, perlu diolah menjadi sediaan untuk meningkatkan minat masyarakat dalam hal konsumsi antioksidan dari bahan alam. Salah satunya adalah dibuat menjadi pastiles. Tujuan dari penelitian ini adalah untuk mengetahui formulasi basis pastiles sebagai model penghantaran sediaan antioksidan yang optimal. Basis pastiles dibuat dengan menggunakan metode molding mixture dengan variasi sukrosa dan sirup glukosa formula 1 (60%:15%); formula 2 (60%: 20%); formula 3 (60%: 25%). Berdasarkan evaluasi basis meliputi uji organoleptik, uji kadar air metode Gravimetri, uji keseragaman ukuran, uji keragaman bobot, uji friabilitas, dan uji waktu larut maka diperoleh basis yang optimal adalah pada formula 1 karena memenuhi seluruh syarat evaluasi pastiles.
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