A 40-year-old man presented at our hospital with anaemia that had been undiagnosed for 2 years. Blood tests, endoscopy, and contrast-enhanced computed tomography were performed, but a definitive diagnosis could not be made. A subsequent bone marrow biopsy revealed basophilic stippling in transformed red blood cells, which led to a differential diagnosis of lead poisoning. Additional tests revealed elevated levels of lead in the blood. Basophilic stippling is generally found on a peripheral blood smear in lead poisoning patients; however, in this case, basophilic stippling was found only on the bone marrow smear and not in the blood smear. Even if basophilic stippling is not found in the peripheral blood, lead poisoning cannot be excluded.

Herein, we report a case of eosinophilia syndrome and deep vein thrombosis presenting concurrently after the administration of the BNT162b2 mRNA‐based coronavirus disease 2019 (COVID‐19) vaccine. It is extremely rare to have both hypereosinophilic syndrome and deep vein thrombosis simultaneously. Both are serious diseases and should be treated with caution.

HANA OTANI ＊1) 9) , AZUSA TAKAHASHI ＊1) 9) , KENICHI KATO ＊2) 9) , NAGAMASA KANO ＊2) 9) , DAIKI WATANABE ＊1) 9) , RISA YOSHIOKA ＊1) 9) , SHOHEI FUJIKAWA ＊3) 9) , TOMOKI HONGO ＊3) 9) , REIKO SUGAHARA ＊4) 9) , MEGUMI HISANAGA ＊4) 9) , YUJI HIRAI ＊5) 9) , TOSHIHIRO MITA ＊6) 9) , KENJI SUZUKI ＊7) 9) , KAZUHISA TAKAHASHI ＊8) 9)

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