The present work was carried out in Private Vegetable Farm at El-Heez, Al-Wahaat Al-Baharyia District, Giza Governorate, Egypt, during two successive summer seasons of 2016 and 2017, to study the effect of plant spacing and apical shoot pinching (ASP) stage on growth and productivity of watermelon plants under sandy soil conditions using drip irrigation system. Results showed that, the interaction between plant spacing at 30 cm and ASP at the 6 th node gave the tallest plants, whereas the interaction between plant spacing at 60 cm and ASP at the 6 th node gave the highest values for each of number of leaves and branches/plant at 45 days after planting. On the other side, planting watermelon at 45 cm and ASP at the 6 th node increased average number of fruits/ plant, average fruit weight, yield/plant and total yield/faddan.