Quantity of castor seed oil (CSO) obtained from local market was determined based on acid value, percentage free fatty acid, iodine value, refractive index, saponification number, specific gravity and moisture content. The CSO was employed in the preparatio resin (oil modified ester) using monoglyceride method. This involved the reaction of the oil with glycerol (alcoholysis) and subsequent reaction of the monoglycride obtained with phthalic anhydride to form the alkyd resin. The CSO and its corres characterized using FTIR. The antimicrobial activity of the alkyd resin was evaluated using paper disc diffusion method. The result showed that prepared alkyd resin is active is active against some selected bacterial srains at conc Sallmonella and Staphylococcus

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