Papillary squamotransitional cell carcinoma is an uncommon histopathological variant of squamous cell carcinoma of the uterine cervix, which occurs in postmenopausal women. A 45-year-old woman presented in the gynae OPD with history of postmenopausal vaginal bleeding with cauliflower like growth in the cervix .Patient was examined and biopsy was taken from the growth which reveal the diagnosis of papillary transitional cell carcinoma cervix on histopathology.

Background: This study was conducted in the Department of Pathology, GMC Patiala on 100 patients over period of three years with the objective to study the comparison of the bone marrow aspiration and bone marrow trephine biopsy in haematological and non-haematological disorders in elderly age patients.(Age >50years). Methods: 100 cases with different hematological and non-hematological problems were taken up for the present study with age >50 years. Salah"s bone marrow aspiration needle and Jamshidi's bone marrow biopsy needle were used to collect the samples. For staining Leishmann's and H&E stains were used. Results: Majority of the cases were in the age of 50-60. Majority of haematological disorders comprised of anaemia (62%), leukemia(17.7%), multiple myeloma (7.5%), primary myelofibrosis(2.5%), myeloproliferative disorders(2.5%), hypocellular marrow (2.5%), increased eoisinophils and precurcors(1.2%), NHL (1.2%) lymphocytosis(1.2%) and plasmacytosis (1.2%). Both of the 2 cases of nonhaematological disorders were of metastatic carcinomatous deposists. Conclusion: The bone marrow aspiration and trephine biopsy were comparative in most of the haematological disorders except in primary and secondary myelofibrosis where biopsy provided clue to the diagnosis. Non-haematological disorders showed the same findings.

Background: Implantation of blastocyst anywhere else, other than uterine cavity is considered as ectopic pregnancy. About 95% of ectopic pregnancies are implanted in the various segments of fallopian tube. Fertilization takes place in the lumen of fallopian tube, from where, aided by the ciliated columnar epithelium of the tube, the fertilized ovum makes its way to the uterine cavity and the implantation occurs. Methods: A study was carried out on 50 patients in the department of pathology, GMC Patiala.to the compare the histopathological and anatomical changes in the lining of the fallopian tube. Results: The routine Haematoxylin and Eosin stain was done and the histopathological study was done. Conclusion: It was concluded that early diagnosis and treatment before rupture still remains the main option of management.

Testicular feminization syndrome is a genetic disorder that makes XY fetuses insensitive/unresponsive to the actions of the androgen hormones .Instead, they are born looking externally like normal girls and internally, there is a short blind pouch vagina and no uterus, fallopian tubes or ovaries. There are testis in the abdomen or in the inguinal canal. The androgen insensitivity syndrome occurs in one out of 20000 births. It can be incomplete (various sexual ambiguities) or complete (the person appears to be a woman). In this case report, a married nulliparous female reported to Gynecology & obstetric dept. for treatment of primary infertility and had history of primary amenorrhea. Physical examination revealed normal external female genitalia with normal breast development (Tanner Stage-5) and absence of axillary and pubic hair. Bilateral adnexal masses were removed and sent for histopathological examination. On microscopic examination both the ovaries revealed seminiferous tubules lined only by the sertoli cells with no evidence of spermatogenesis. No ovarian tissue seen.

Haemoglobin SD -Punjab is a rare compound heterozygous haemoglobinopathy characterised by presence of two beta globin gene variants : beta 6(GAG to GTG) and beta 121(GAA to CAA). These patients' clinical and haematological features mimic haemoglobin S disease. This case highlights the propensity for occurrence of rare phenotypes and emphasises the importance of accurate diagnosis especially during ANC checkup and to plan an effective patient management strategy before complications evolve.