A 22-year-old female in her third trimester of pregnancy was referred to our department for sudden loss of vision with a painful blind eye. It was diagnosed as retinoblastoma clinically and radiologically. Histopathology and immunohistochemistry confirmed the diagnosis. This case is one of its kind because retinoblastoma occurring during pregnancy had not been reported in literature so far.
A 23 yr old male presented with itching, watering, redness, discharge and photophobia in right eye since 5 yrs, with exaggerated symptoms since 2 months. Slit lamp examination revealed shield's ulcer in right eye. Topical and oral medications were started. Patient had recurrent giant papillary conjunctivitis and shield's ulcer in spite of intense topical and oral medications. In December 2018, he underwent liquid nitrogen cryotherapy, performed in right eye first using double freeze thaw technique followed by left eye 2 months later. His symptoms resolved, giant papillae attenuated and corneal luster improved and he is doing well after 6 months follow up.
Neoscytalidium dimidiatum is a plant pathogen that rarely causes human infection. Very few cases of ocular infection have been reported. We report a case series of three patients who presented with keratitis caused by it. The culture showed effuse, white-to-grayish colonies with yellow-to-deep orange colony reverse. Chains of arthroconidia typical of Neoscytalidium were seen on staining with lactophenol cotton blue. Two patients responded to topical antifungal treatment while one needed therapeutic keratoplasty. Hence, early diagnosis and intensive antifungal treatment are essential for successful healing in mycotic keratitis caused by Neoscytalidium species.
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