Tetra(o-tolyl)diborane(4), 1, was synthesized and characterized experimentally as well as theoretically by density functional theory (DFT) calculations. Exposure of 1 to H (1 bar) at room temperature afforded the corresponding di(o-tolyl)hydroborane through cleavage of the H-H and B-B bonds. DFT calculations suggested a diarylboryl anion character for the transition state.

The reaction of highly Lewis acidic tetra(o-tolyl)diborane(4) with CO afforded a mixture of boraindane and boroxine by the cleavage of the C≡O triple bond. C labeling experiments confirmed that the carbon atom in the boraindane stems from CO. Simultaneously, formation of boroxine 3 could be considered as borylene transfer to capture the oxygen atom from CO. The reaction of diborane(4) with Bu-NC afforded an azaallene, while the reaction with Xyl-NC furnished cyclic compounds by direct C-H borylations.

The reaction of highly Lewis acidic tetra(o‐tolyl)diborane(4) with CO afforded a mixture of boraindane and boroxine by the cleavage of the C≡O triple bond. 13C labeling experiments confirmed that the carbon atom in the boraindane stems from CO. Simultaneously, formation of boroxine 3 could be considered as borylene transfer to capture the oxygen atom from CO. The reaction of diborane(4) with tBu−NC afforded an azaallene, while the reaction with Xyl−NC furnished cyclic compounds by direct C−H borylations.

This study was conducted to evaluate the clinical outcomes of 53 patients with T3N0M0 larynx squamous cell carcinoma in our hospital between May 2006 and March 2019. The subjects were 48 men and 5 women, ranging in age from 47 to 88 years, with mean age of 72 years. The treatment was surgery in 26 patients, chemoradiotherapy (CRT) in 17 patients, and radiotherapy alone (RT) in 10 patients. The 3-year overall survival (OS) rate was 79.2％, and the 3-year disease-specific survival (DSS) rate was 84.4％.The total 3-year larynx preservation rate was 37.3％, 48％ for RT cases, and 81.6％ for CRT cases.Treatment with chemoradiotherapy improved larynx preservation rate versus radiotherapy alone (p＜ 0.05) . The 3-year OS rate was 82.2％ for surgery cases, 94.1％ for CRT cases, and 48％ for RT cases. Our therapeutic approach of using surgery or CRT showed successful outcomes for OS and DSS.

We present a case of acute bilateral suppurative parotitis in an elderly patient with acute heart failure who was hospitalized and treated with noninvasive positive-pressure ventilation. In this case, sepsis due to infection occurred, leading to severe illness.