Background: E. faecium infections are increasingly refractory to antibiotics, encouraging vaccine approaches. Results: Structures of novel protective surface polysaccharides and a teichoic acid were identified from a multidrug-resistant strain. Conclusion: Detection of these antigens on diverse clinical strains predicts broad coverage for a potential multivalent vaccine. Significance: Results suggest the feasibility of a glycoconjugate vaccine to prevent E. faecium disease.

Fig. 1), and multiple small, shallow ulcers in the rectum (• " Fig. 2). Pathologic examination of biopsies showed exudates with necrosis, and pieces of colonic mucosa with severe acute and chronic inflammation, and focal acute cryptitis, plus multiple vacuolated and amoeboid structures (• " Fig. 3). Subsequent stool study with a special trichrome stain confirmed the diagnosis of Blastocystis hominis. He was treated with metronidazole for 10 days with symptom resolution, and no recurrence of diarrhea.

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1 is reported. In the solid-state conformation of 1, the dihedral angle about the C C sp 2 -sp 2 σ bond connecting the two aryl rings is 50.1 • . The observed C 2 symmetry in the solid-state conformation of 1 is consistent with the previously suggested solution conformation.