Background: Green tea, is one of the herbs that have been proven to be effective as an anti-acne, among others.Green tea leaves contain 30-40% polyphenols known as catechins most of which are antimicrobial. For ease of use, the ethanolic leaf extract of green tea is made in cream. This study aimed to determine the effect of variations in the concentration of ethanolic extract of green tea leaves in cream on the physical properties and antibacterial activity of acne bacteria in particular.Design and Method: In this study, green tea leaf extract condensed obtained by maceration using 50% ethanol solution. Cream formula that is made in five concentration ethanolic extract of green tea leaves 1%, 3%, 5%, 7%, and 9% use a modified formula antiacne cream. Cream tested physical properties include homogenity, percent separation, dispersive power and adhesion. During the antibacterial activity was also tested. The data obtained were analyzed statistically using the non-parametric Kruskal-Wallis test followed by Mann Whitney test with a level of 95%.Results: The preparation cream ethanolic leaf green tea extract at various concentrations have good homogenity and not separate, the greater concentration of cream ethanolic extract of green tea leaves get smaller power and energy dispersive adhesion, whereas the inhibitory against Staphylococcus aureus bacteria is getting biger. Conclusion: Cream ethanolic extract of green tea leaves that are comparable with the positive control (Ristra acne creaming) the physical properties and the antibacterial activity at a concentration of 7% (Sains Medika, 4(2):147-156).
The dregs of green tea leaves have not been used until today, it is still considered as a waste that is not useful. It is known that the dregs of the green tea leaves contain Epigallocatechin-3-gallate (EGCG), which is quite high. EGCG has benefits as an antibacterial. The long-term goal of this research is the application of cosmetic preparation products from the dregs of green tea leaves that have effectiveness, stability and high economic value. The specific target of this research is to get the dose and concentration of the dregs of green tea leaves in a stable and effective way as anti-acne against Staphylococcus epidermidis (S. epidermidis). The search of the dregs of green tea leaves is by techniques of infundation of liquid fractions with ethyl acetate, identification of EGCG compound by using HPLC, antibiotics test against S. epidermidis was conducted by diffusion method. The results showed that the content of EGCG of the dregs of green tea leaves was 21.325% w/w, and the concentration of 1% of the dregs of green tea leaves can inhibit the growth of S. epidermidis well.
Central Java is one of the contributors to our maternal and infant mortality rates in Indonesia. This increase was partly due to the knowledge of pregnant women about nutritional needs at the time of assessment. The purpose of this research is to increase the knowledge of pregnant women about the adequacy of nutrition and the use of drugs during pregnancy. The method used was assistance for pregnant women by professionals in their fields in September Obgyn Doctors and Pharmacists and descriptive analysis through questionnaires before and then conducted activities. Assistance activities carried out for one day in preparation for preliminary pregnant women in Pudak Payung. Based on the results of research people do not understand the importance of adequate nutrition during the assessment seen from a baby's low weight at his age. After mentoring, the increase in knowledge and awareness of pregnant women increased by 97%. Abstrak Jawa tengah merupakan salah satu penyumbang angka kamatian ibu hamil dan bayi di Indonesia. Peningkatan tersebut salah satunya karena faktor pengetahuan ibu hamil mengenai kebutuhan gizi pada saat kehamilan. Tujuan dilakukan penelitian adalah meningkatkan pengetahuan ibu hamil akan kecukupan gizi dan penggunaan obat selama kehamilan. Metode yang digunakan adalah pendampingan pada ibu hamil oleh tenaga professional dibidangnya seperti Dokter Obgyn dan Apoteker dan analisa deskriptif melalui kuisioner sebelum dan sesudah dilakukan kegiatan. Kegiatan pendampingan dilakukan selama satu hari sebagai gambaran pendahuluan kondisi ibu hamil di Pudak Payung. Berdasarkan hasil penelitian masyarakat belum mengetahui akan pentingnya kecukupan gizi selama kehamilan dilihat dari berat badan bayi yang rendah pada usianya. Setelah dilakukan pendampingan peningkatan pengetahuan dan kesadaran ibu hamil meningkat sebesar 97%.
Interaksi antar obat adalah kondisi ketika pemakaian obat dapat memberi dampak dari obat lainnya secara farmakokinetik ataupun farmakodinamik. Dampak yang ditimbulkan akibat interaksi antar obat berupa efek yang diharapkapkan ataupun efek yang tidak menguntungkan bagi pasien. Pada umumnya interaksi obat terjadi pada pasien diabetes melitus karena mendapatkan terapi pengobatan lebih dari satu macam obat sehingga berpeluang terjadi interaksi yang akan mengganggu pengendalian kadar gula. Penelitian ini bertujuan untuk melihat adanya hubungan interaksi antar obat dengan kadar gula darah. Jenis penelitian ini bersifat observasional, dengan menggunakan rancangannpenelitian analitik dengan pengambilan data secara retrospektif. Populasi dalam penelitian ini adalah seluruh pasien rawat inap diabetes melitus dengan atau tanpa penyakit penyerta hipertensi, dislipidemia, dispepsia, congestive heart failure, dan coronary artery disease di Rumah Sakit Islam Sultan Agung Semarang. Sampel yang diambil sebanyak 51 pasien dengan Teknik pengambilan purposive sampling. Data diambil dengan pengumpulan data rekam medis pasien rawat inap yang kemudian dilakukan analisis statistika menggunakan uji Chi-Square untuk mengetahui hubungan interaksi obat dengan profil glikemik. Berdasarkan analisis statistik di dapatkan hasil nilai p-value 0,001 sehingga dapat disimpulkan terdapat hubungan interaksi pengobatan dengan dengan kadar gula darah pada pasien diabetes rawat inap di Rumah Sakit Islam Sultan Agung Semarang.
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