No abstract

The first stereocontrolled and enantiospecific formal synthesis of antiplatelet drug beraprost has been achieved from readily available 1-tetralone.

The total synthesis of (-)-α-Kainic acid is accomplished using a linear strategy involving Noyori asymmetric reduction and chirality transfer through Ireland-Claisen rearrangement as key steps.

Internal alkynes are readily oxidized to the corresponding diketones under conditions A). The latter can be directly converted to quinoxalines in a one-pot procedure. -(CHANDRASEKHAR*, S.; REDDY, N. K.; KUMAR, V. P.; Tetrahedron Lett. 51 (2010) 28, 3623-3625,