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Segmentation of lung regions with lung nodules at mediastinum is the first step in computer-aided detection (CAD) which provides a better diagnosis of lung cancer. The existing methods fail in segmentation of lung regions with the cancer tumors at the mediastinum of the lungs. In this paper, a new approach is proposed that extracts lung regions with cancer tumors at the mediastinum of the lungs based on curve analysis. The proposed algorithm is tested on 05 patient's dataset which consists of 60 images of the Lung Image Database Consortium (LIDC) and the results are found to be satisfactory with 99 % average overlap measure (AΩ). The proposed algorithm extracts lung nodules at the mediastinum of the lungs which helps in detection of lung cancer.

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