The pandemic COVID-19 is the most terrible calamity of the present human history also it has led to the worldwide issue of public health as a primary health safety problem. It was assumed that the infection of COVID -19 has two-phases, the immune protective as well as damaging phase. In the immune protective phase, clinicians try to enhance the patient immune response, and in the immune damaging phase, clinicians try to control the inflammatory immune response. Zinc belongs to the d-block or a transition element, it is an indispensable trace metal needed for vital cell activities like growth, as well as cell survival. It has significant contributions to immune homeostasis and functions; zinc inadequacy reduces primary and secondary immune responses equally. Studies have shown people who are deficient in zinc are more susceptible to infection. An inclusive knowledge of the bioavailability of the transition metal Zinc will help to be aware of those that are valuable and protective for the population's health. This work is concentrated on the significance of Zinc for the immune function, the presence of it’s in optimum amounts, and how it is beneficial to health in general and in fighting with COVID 19 in particular until today.