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<b> Introduction:</b> Anastomotic leak after colorectal surgery is a serious complication that causes significant postoperative morbidity and mortality. </br></br> <b>Aim:</b> This study aimed to investigate the predictive value of increased postoperative carcinoembryonic antigen (CEA) in early intestinal anastomosis leakage in patients who underwent right hemicolectomy surgery.</br></br> <b>Material and methods:</b> In this prospective study, 535 patients who underwent right colon cancer surgery with stapled anastomosis were enrolled. A subset of 315 patients was included in the study after meeting the inclusion criteria. Preoperatively, their serum CEA levels were measured, and on postoperative days 3 and 6, the levels were measured again.</br></br> <b>Results:</b> Early AL occurred in 18 patients (5.71%). The mean ± SD age of patients was 65.06 ± 11.69 years. Increased CEA level was associated with increased odds of intestinal AL among the patients after three and six days of surgery (OR after three days = 1.3; 95%CI = 1.1–1.5, OR after six days = 1.7 95%CI = 1.14–2.5). The mean CEA level significantly increased among patients with anastomose leakage (P-value < 0.001). </br></br> <b>Conclusion:</b> The results showed that increasing CEA levels can be used as one of the non-invasive markers in detecting early AL in patients with right colon cancer surgery.

Background & Aims: Colorectal cancer is one of the most common cancers of the gastrointestinal tract, caused by predisposing factors like lifestyle and aging, and partly, due to genetic and inherited disorders. Due to the increasing incidence of this cancer in Iran, the present study was designed to determine the prevalence of osteoporosis and its relationship with serum levels of vitamin K2 in the patients with colon cancer before and after colectomy. Materials &Methods:In this descriptive-analytical study, 38 patients with colon cancer who underwent colectomy in Imam Khomeini Hospital in Urmia were included in the study. Demographic information, BMD, and vitamin K2 levels of the patients before and after colectomy were collected and recorded in a checklist. Data were analyzed using SPSS Version 17 statistical software. Results: From 38 patients with colorectal cancer, 34.2% were male and 65.8% were female. The mean age of the patients was 58.5 ± 12.7 years. Reviewing bone density examinations done by Dual Energy X-Ray Absorptiometry (DXA) in hip and spine of the patients showed that osteoporosis was higher in both places after colectomy, and their significant differences between them (P-Values were 0.043 for hip and P0.009 for spine). Conclusion:The results of this study showed that osteoporosis in the hip and spine of the patients with colon cancer increased after colectomy compared to it before colectomy. However, the correlation between serum vitamin K2 levels and osteoporosis was not significant.

Proliferating trichilemmal tumor (PTT) is a scarce tumor of exterior root sheath that appears to grow within the wall of a pre-existing pilar cyst in most cases. This report presents a case of malignant PTT in the posterior sacrum of a 33-year-old man presenting with limited mobility and a history of paraplegia.