Background: Amniocentesis, like other invasive methods, has complications such as abortion, premature rupture - second pregnancy and at 29 weeks of membranes, infection, bleeding, etc. Here, we aimed to study the complications of amniocentesis in pregnant women. Methods: This descriptive cross-sectional study was included 409 women with positive first and second stage screening or required amniocentesis referred to Baghaeipour Clinic in 2017. Data was collected by a pre-prepared questionnaire. Results: The mean age of the patients and gestational age was 33.49 ± 6.51 years and 17.39 ± 1.36 weeks, respectively. 132 patients (32.2%) had a history of abortion. Regarding the frequency of needle passage through the placenta, the results showed that in 369 people (90.2%) the needle did not pass through the placenta and in 40 people (9.8%). The needle has passed through the pair. Regarding the frequency distribution of amniocentesis complications, fetal death in (2.4%), bleeding in (2.2%) and PROM (1.7%) were observed in patients and no case of infection and abortion was observed. In terms of age, gestational age, gestational number, placental location, needle passage, aspirated fluid color, history of abortion and type of delivery, there were no significant differences. Conclusion: In this study the most common complication of amniocentesis was fetal death (2.4%), followed by bleeding and Spotting (2.2%), PROM (1.7%), infection and abortion, respectively.
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