The purpose of the study involves the presentation of a methodological approach to planning in the management system of innovative and production activities of enterprises for the sustainable economic development of the region. To achieve the goals set, a number of methods were used that formed the research methodology. The main practical method that was used is the method of functional modeling and graphical demonstration of the process. The method is a modeling technique with specific goals and sub-processes to achieve it (IDEF). The results of the study demonstrated the formation of decompositions of models, each of which offers certain areas for improving planning in the management system of innovative and production activities of enterprises for the sustainable economic development of the region. The model was presented in the practice of several enterprises in a particular region. The model has all the principles of effective application for the implementation of the planning function in the management system of innovative and production activities of enterprises for the sustainable economic development of the region. Originality is manifested in the application of existing methods in a new field.