Aim: To study the anamnesis, development parameters and health condition in the first year of life of the children conceived by IVF. Materials and Methods: 116 children born by IVF and 46 children born in natural pregnancy were examined. Results: In most cases of our study, children after IVF were born prematurely from women with a bad obstetric and gynecological history and had a low birth weight. The period of early adaptation in premature infants born after assisted reproductive technologies was complicated by respiratory distress syndrome. Most often the children after IVF had such pathologies as central nervous system damage, deficiency anemia and minor anomalies of heart development in the neonatal period. Compared with children born in natural pregnancy, infectious diseases were more often detected in newborns after IVF. The development of bronchopulmonary dysplasia was significantly more frequent in children after IVF within a month of life. At six months, most of the IVF babies had low parameters of physical development, whereas weight and growth indicators did not differ significantly from the general population indicators by the first year of life. Most of the children born after IVF had neurological outcomes, such as delayed psychomotor development, malfunctioning of the autonomic nervous system, convulsive syndrome by the year of life. Conclusion: Children born after IVF have features of somatic status, neuropsychiatric and physical development, which indicates the need for targeted monitoring and continued research in this group of children to minimize health risks.

Clinical signs of systemic connective tissue dysplasia in children with acute and recurrent torticollis were studied. 225 clinical cases were analyzed. The predominance of joint hypermobility and asthenic physique in the group of children with recurrent torticollis was revealed and proved by the medical statistics methods. In this group, such skeletal clinical forms as flat-valgus deformity of the feet, kyphosis, scoliosis were observed.

The paper presents the results of a study of iron metabolism in full-term infants conceived naturally and using in vitro fertilization (IVF) technology. The data obtained allowed us to conclude that there were no statistically significant differences in the studied indicators in the groups and did not reveal the effect of IVF technology on the iron metabolism of full-term newborns. The purpose of the study. To study and compare the data of iron metabolism - hemoglobin, serum iron, serum transferrin recep-tor (sTfR), ferritin, ferritin index (sTfR/logFer), transferrin saturation, zinc protoporphyrin/ heme ratio in full-term infants conceived using IVF technology and children born by natural conception. Materi-als and methods. Clinical, biochemical and statistical methods were used in the work. The indicators of hemogram and ferrokinetics were determined in 20 full-term children conceived by observation, and in 18 children born using the technology of in vitro fertilization. Research results. In full-term children born as a result of IVF procedure, the level of Hb it was 17,03 ± 0,82 g/dl. The level of serum iron was comparable in the study groups (in full–term children conceived naturally, it is 26,09 ± 0,68 μmol/l, in children conceived by IVF – 25,24 ± 0,5 μmol/l). Studies of the ferritin level in full–term children conceived in the traditional way showed values of 175,73 ± 11,63 μg/l, in children after IVF procedure – 177,04 ± 11,21 μg/l. When calculating the ferritin index (sTfR / log10 Ferritin), data were obtained - in full-term children, the ferritin index is 3,72 ± 0,28 and 4,03 ± 0,36 mg/l depending on the method of conception, the differences are not statistically significant. In full-term children conceived naturally, the TS level was determined to be 61,18 ± 4,11 %, and in full-term children born as a result of traditional conception – 61,77 ± 5,3 %. Conclusion. The study allowed us to conclude that there is no statistically significant effect of the IVF method on iron metabolism and ferrokinetic factors in full-term newborns conceived by this method.