Tobacco use is strongly associated with cardiovascular disease and the only avoidable risk factor associated with development of aortic aneurysm. While smoking is the most common form of tobacco use, snuff and other oral tobacco products are gaining popularity, but research on potentially toxic effects of oral tobacco use has not kept pace with the increase in its use. Here, we demonstrate that cigarette smoke and snuff extracts are highly toxic to developing zebrafish embryos. Exposure to such extracts led to a palette of toxic effects including early embryonic mortality, developmental delay, cerebral hemorrhages, defects in lymphatics development and ventricular function, and aneurysm development. Both cigarette smoke and snuff were more toxic than pure nicotine, indicating that other compounds in these products are also associated with toxicity. While some toxicities were found following exposure to both types of tobacco product, other toxicities, including developmental delay and aneurysm development, were specifically observed in the snuff extract group, whereas cerebral hemorrhages were only found in the group exposed to cigarette smoke extract. These findings deepen our understanding of the pathogenic effects of cigarette smoking and snuff use on the cardiovascular system and illustrate the benefits of using zebrafish to study mechanisms involved in aneurysm development.

Badanie eksploracyjne zrealizowane na zlecenie Centrum Komunikacji Społecznej Urzędu m.st. Warszawy w ramach zajęć IV edycji Programu Wolontariatu Badawczego prowadzonego przez Uniwersyteckie Centrum Wolontariatu. IV edycja była finansowana Ryc. 30. Podział miejskich form służących do siedzenia (opracowanie własne: Maja Skibińska) W tym miejscu warto podkreślić, że cechą komfortowej przestrzeni miejskiej jest według Gehla występowanie w niej rozmaitych miejsc do siedzenia. Jego zdaniem cała przestrzeń publiczna powinna przypominać "krajobraz do siedzenia", czyli zapewniać rozmaite możliwości siedzenia. Cele badań Cel badawczy Za cel badawczy obraliśmy sobie określenie potrzeb użytkowników dotyczących funkcjonowania, ilości, lokalizacji oraz wyglądu miejsc do siedzenia w przestrzeni publicznej. Uszczegółowienie celu głównego:-charakterystyka ławek, które są elementem integrującym ludzi na miejskich placach (perspektywa pierwsza: potencjał więziotwórczy);-określenie, w jaki sposób charakter otoczenia, sposób zagospodarowania placu oraz jego wyposażenie wpływają na chęć korzystania z ławek (perspektywa druga: otoczenie ławki a chęć korzystania z niej);-zbadanie ławek dedykowanych seniorom w przestrzeniach tranzytowych (perspektywa trzecia: seniorzy w przestrzeniach tranzytu). Cel aplikacyjny Celem aplikacyjnym było sformułowanie wytycznych do projektowania miejsc do siedzenia na warszawskich ulicach i placach.

Apart from conventional treatment, dentists are increasingly relying on physical therapy modalities in their clinical practice. The aim of this literature review is to analyze the clinical relevance and potential uses of ozone in modern dentistry. The research question is geared towards detailing the multiple potential applications of ozone therapy in a range of dental specialties. Based on the available literature, accessed via the PubMed, Google Scholar, Scopus, and EBSCO databases, a detailed search of the electronic literature was performed for 2001–2022. Eligible studies were chosen according to inclusion and exclusion criteria, using keywords: ozone, ozone therapy, therapeutic applications, oxidants, dental disinfectants, oral medicine, physical therapy in dentistry. Out of 834 manuscripts, 273 studies were curated. A total of 70 publications were used in the final consideration. After assessing their quality, they were analyzed to determine the relevance and potential use of ozone in the various aspects of modern dentistry. Ozone therapy is used mainly as an adjunct to the primary clinical or pharmacological treatment. In some cases of oral mucosal disease, it has proven effective as a primary therapy. During the literature analysis, it was noted that ozone therapy in dentistry is a subject of ongoing research, and the results are not always consistent. The multitude of studies in the literature on the applications of ozone in dentistry reflects the search for its undiscovered physical therapeutic potential.

In this article we analyse local community-based concepts and practices related to establishing a new middle-class identity when under social and “environmental” pressure. We based our ethnographic inquiry in “RA” – a Warsaw suburb – well-known as a former village but now a location for industry and waste-processing plants. Its vicinity, despite being populated, is polluted by heavy traffic, noise and an unpleasant odour, all of which recently have become the stimulus for social mobilisation and intense criticism toward the local authorities and an inconsiderate urbanisation policy. A key role here is played by two organisations, both exerting a strong influence on the new middle/creative class living in gated communities – a novel phenomenon for the local sociocultural landscape. We argue that this activism and struggle for a clean environment is rooted in the post-1989 Polish politico-economic transformation and the emergence of new middle-class identity projects. Thus, we reveal that sustainable urbanisation and “green policies” in Poland are embedded in middle-class identities, and gain momentum especially when class identity and image are under threat.

Horacio Castellanos Moya es uno de los autores más interesantes y originales que en las últimas dos décadas han marcado su presencia en el campo de la narrativa hispanoamericana. En una de las entrevistas concedidas, el autor salvadoreño afirmó que escribe “desde la infelicidad”: producto de la experiencia del terror de la guerra civil, de la desilusión con la especie humana y del sentimiento de desarraigo. Las experiencias mencionadas han dejado huella en su narrativa, influyendo en la temática de sus textos y en el lenguaje que emplea. Por tanto, el objetivo del presente trabajo consiste en acercarse al peculiar estilo de la prosa de Castellanos Moya –perteneciente a la llamada narrativa post-testimonial–en la que los sentimientos como la rabia, la nostalgia o la indignación son expresados mediante un vasto abanico de herramientas literarias.