The aim: To increase the effectiveness of treatment of sinusitis polyposa patients, develop and introduce a new non-traditional complex method of influencing several links of the pathogenesis of this disease, including laser therapy and laser puncture, used in the postoperative period. Materials and methods: In 60 rhinosinusitis polyposa patients the indicators of lipid peroxidation and the state of antioxidant protection were studied. Depending on the type of treatment, the patients were divided into two groups: the first included 30 people who underwent traditional surgical intervention, and the second – 30 people who used complex therapy, including in the postoperative period endonasal laser exposure and laser puncture. Methods: clinical data, the functional state of the nasal mucosa, indicators of lipid peroxidation (hydroperoxide, malondialdehyde) and antioxidant activity (glutathione peroxidase, glutathione reductase, reduced glutathione, superoxide cismutase, catalase) of erythrocyte membranes and blood serum were studied. Results: The proposed complex method for treating lipids of erythrocyte membranes and serum, which includes endonasal surgical intervention, endonasal laser therapy and laser puncture leads to the normalization of physiological functions of the nose, activates antioxidant protection and reduces the peroxide activity of lipids in the membranes of erythrocytes and blood serum. Conclusions: When examining patients in the long-term (after 1 year) period, a significant improvement in 85.7% of cases, an improvement in 10.7%, and absence of effect in 3.6% was achieved. Thus, the proposed method of therapy can be recommended for widespread use in medical institutions.
Strangulation asphyxia (SA) is one of the types of acute airway obstruction that occurs during direct compression of the trachea, blood vessels and nerve trunks of the neck. Characteristic of this type of asphyxia are rapidly growing hypoxemia and hypercapnia, deep disturbances of cerebral circulation by hemorrhagic type, hypoxic/anoxic encephalopathy. There are three main categories compression of the neck: hanging, ligature strangulation, suffocation by hands. The difference between these three concepts is explained by the cause of the external compression of the neckeither a tightening strip tensed by the gravitational weight of the body, or by part of the body; tightening strip provided by a force other than body weight (ligature strangulation); or external pressure by the arms, forearms, or other limbs (suffocation by the hands). "Hanging in falling from height (with a jerk)" is not a typical form of strangulation asphyxia and is not a suffocation subtype. The main clinical signs of strangulation in dependence to its duration: in the overwhelming majority of victims who were brought to the hospital alive, the level of consciousness by the Glasgow scale was defined as <8. In most of the surviving patients this indicator was more than 3 points. Obstruction of venous outflow from the brain leads to congestive hypoxia and loss of consciousness in just 15 seconds. Complications of strangulation asphyxia: post-hypoxic/post-anoxic encephalopathy; cases of temporary vision loss are known, in a number of cases-"tympanic membrane syndrome"; chondroperichondritis; damage to the cervical spinal cord is accompanied by appropriate neurological symptoms in the form of
The article provides a form of performing a fragment of scientific work by interns, which motivates a young doctor to study modern methods of diagnosis and treatment in various sections of otolaryngology. It provides for the study of an important modern issue in the specialty, attending online conferences on the selected topic and a thorough study of international literature over the past 3 years. Control over the implementation is carried out by all employees of the department through a presentation of the scientific work and defense of these by an intern doctor.
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