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The article shows effectiveness of toxicants elimination in pre-school and junior school children from the zones of slow and quick metabolism. Created by us technology gave the following results. Special physical loads stimulate lead elimination in the zone of slow metabolism, the increased concentration of nickel normalization in children of different gender, the increased concentration of chromium and manganese in boys; in the zone of quick metabolism – zinc, chromium, cobalt, manganese among children of different gender, moreover they stimulate the elimination of benzene, deposited ethylbenzene, toluene and formaldehyde.

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The harmful influence of the environment on health is known. Millions of tons of chemical compounds are released into the environment every year. In the soil when planting various plants, a huge amount of mineral fertilizers, as well as poisonous substances to fight weeds are introduced. Harmful substances enter the body with air, water and food. Air pollution has a harmful effect on humans, especially on the lungs, which serve as a filter to protect the body from airborne toxicants and poisons. With a large concentration of harmful substances in humans, poisoning is observed. With severe poisoning, the overall morbidity increases, as well as the respiratory system.The study involved children from one of the ecologically disadvantaged regions of the Russian Federation with health disorders-60 girls and 90 boys. The paper uses such research methods as analysis and synthesis of literary sources, atomic absorption analysis, pedagogical experiment, anthropometry, spirometry, analysis of documentary sources, methods of mathematical statistics, etc. The results of the research showed that children living in environmentally unfavorable places have reduced indicators of physical health and functional status: heart rate, lung capacity; breath retention on inhalation and exhalation. The concentration of lead in the body of children is increased several times. Directed physical activity, used in an environmentally relatively clean place, contribute to the excretion of lead from the body of children. The correlation between the number of trips in insulated clothing and a decrease in the content of lead in the hair of children was revealed: the correlation coefficient is 0.81 in girls, 0.92 in boys. For unloading of solid biological means of children organism from lead the most rational are occupations in the pool in a complex with thermal air influences (for girls) and land loadings in the warmed clothes in a combination with thermal air (for boys).