International audienceAn efficient palladium-catalyzed [2 + 1]cycloaddition between ynamides and norbornenes or norbornadienes is reported. Both phosphapalla- dacycles and palladium/secondary phosphine oxide catalytic systems were found to be competent for the transformation allowing the preparation of ami- nomethylenecyclopropanes. The reaction showed general applicability to various functionalized bicyclo[2.2.1]hept-2-enes and ynamides. A chiral phosphapalladacycle was tested to carry out this transformation in an enantioselective fashion

Palladium-Mediated [2 + 1] Cycloaddition of Norbornene Derivatives with Ynamides. -The title reaction shows general applicability to various functionalized bicyclo[2.2.1]hept-2-enes, such as (I), (IV), (VII), (IX), and (XI) and ynamides. -(CLAVIER*, H.; LEPRONIER, A.; BENGOBESSE-MINTSA, N.; GATINEAU, D.; PELLISSIER, H.; GIORDANO, L.; TENAGLIA, A.; BUONO, G.; Adv. Synth. Catal. 355 (2013) 2-3, 403-408, http://dx.doi.org/10.1002/adsc.201200903 ; Cent. Marseille, Univ. Aix-Marseille III, F-13397 Marseille, Fr.; Eng.) -S. Karsten 30-066