No abstract

The purpose of this study was to study the immunomodulatory and clinical properties of the Georgian drug “LAZOLEX” in patients with Recurrent Aphthous Stomatitis (RAS). Clinical and Immunological parameters were studied in 50 patients, the results showed the correlation between the condition of immune system and the severity of the RAS, i.e., the most severe immunosuppression was recorded in patients with severe stomatitis. 5% Gel of “LAZOLEX” compared to traditional therapy, showed the same high clinical activity, but the presence of immunocorrective properties in LAZOLEX manifested itself in an improvement in the quality of patient treatment: decrease of time of epithelization and a significant increase in the duration of remission. Conducted clinical, laboratory and immunological studies allow us to recommend LAZOLEX for active use in dental practice for RAS.

No abstract

Discoid Lupus Erythematosus is usually localized on the open areas. On the scalp it causes dilatation and plugging of hair follicles with adherent scales, this leads to destruction of hair follicles and permanent alopecia. Initial manifestation of disease can be difficult to recognize. Early visit to Dermatologist is recommended. Differential diagnosis of scarring alopecia include trauma, burn, tinea capitis, lichen planus, scalp psoriasis, sarcoidosis and alopecia areata.

Cancers of the oral cavity represent a significant worldwide health problem. Despite the general accessibility of the oral cavity during physical examination, many malignancies are not diagnosed until late stages of disease. A wide array of conditions has been implicated in the development of oral cancer, including leukoplakia, erythroplakia, palatal lesion of reverse cigar smoking, oral lichen planus, oral submucous fibrosis, discoid lupus erythematosus, and hereditary disorders such as dyskeratosis congenital and epidermolysis bullosa.In order to prevent malignant transformation of these precursor lesions, multiple screening and detection techniques have been developed to address this problem. The early detection of cancer is of critical importance because survival rates markedly improve when the oral lesion is identified at an early stage.