Background: Papacarie pre-treatment of dentin surface has been reported to exhibit good bond strength values between dentin and composites. Its desirable properties like high pH, sites specify and anti-inflammatory response makes it a future material in place acid etching pre-treatment. Acid etching may cause sensitivity and collapse of dentinal matrix. Methods: This in-vitro study involved, 60 caries free extracted premolars, randomly divided into three groups. Control Group (Group A) No pre-treatment of dentin prior adhesive application. Experimental Group B acid etchant was applied before adhesive application. Experimental Group C Papacarie was used as a pre-treatment agent. All these specimens were tested for shear bond strength with the help of Universal Testing Machine. All the collected data was entered in SPSS version 20.0. ANOVA was used to determine the mean SBS (Shear Bond strength) values of control and experimental groups. Results The mean shear bond strength of material was 7.74±0.47 in group A, 17.80±1.43 in group B and 15.11±0.70 in group C. Group B showing better strength than other two groups. Conclusion: The study provides information about longevity of composite restorations and may help in extending the clinical usage of papacarie to avoid harmful effects of acid etching on dentin and pulpal tissue.

Objective: This study aimed to assess in vitro bioactivity of novel remineralizing dental composites loaded with calcium phosphate fillers and chlorhexidine in polypropylene glycol (PPG) resin matrix. Methods: The stock monomer was prepared by adding 69.75% urethane dimethacrylate and 23.25% of the polypropylene glycol dimethacrylate with silica fillers, chlorhexidine (5 wt%), and varying levels of calcium phosphate fillers. The study groups were BC (basic composite), commercial control, CHX-CP5, CHX-CP10, and CHX-CP15, respectively. Bioactivity was assessed by placing samples in the simulated body fluid (SBF) for 7, 14, and 28 days and observed under the scanning electron microscope and energy dispersive X-ray spectroscopy. Data were presented in mean and percentage with a 95% confidence interval. Intergroup analysis was performed using one-way ANOVA and the p-value was set ≤0.05. Results: The SEM images showed the deposition of calcium phosphate on the surface of CHX-CP10 and CHX-CP15 after 28 days in SBF. Mineral deposits of calcium and phosphate were observed on the surface of the experimental formulation containing higher calcium phosphate fillers (CP10 and CP15) in EDX. Conclusion: The addition of calcium phosphate fillers to the composites resulted in an apatite layer formed and demonstrated enhanced bioactivity in the presence of PPGDMA and CHX.