Antibacterial resistant bacteria cause a big concern to poultry and to public health in general because some bacterial poultry pathogens can infect humans or transfer their resistance ability to human pathogens. Nontherapeutic use of antibacterial in poultry, especially as growth promoters to increase feed conversion efficiency is thought to be one of the main causes of resistance. The study included pulmonary swab samples collected during necropsy from 120 poultry farms showing respiratory symptoms with mortality. The disc diffusion method for antibiotic sensitivity testing was performed and antibiotic disks for 21 antibiotics were used. The results showed that three antibacterial were sensitive to more than 50% of the isolates. The first is doxycycline and 69.9% of the isolates were sensitive. The second is Cefalexin with 60.5% sensitive isolates and third is Chloramphenicol with 55.2% sensitive isolates. In the rest of antibacterial, less than 50% were sensitive. Five isolates were found resistant to all antibacterial. Moreover, three samples were found to be negative with no bacterial growth. The present study concluded that 50% of the aerobic bacteria isolated from poultry lungs are resistant to 85% of the 21 antibiotics tested in the study.

Infectious bursal disease (IBD) is a viral disease causes increased mortality and severe immunosuppressionin commercial chickens. The virus infects the bursa of Fabricius of particularly the actively dividing and differentiating lymphocytes of the B-cellslineage of young chickens, resultant in morbidity, mortality, and immunosuppression. Immunosuppression enhances the susceptibility of chickens to other infections and interferes with vaccination against other diseases. Immunization is the most important measure to control IBD; however, wild usage of live vaccines has resulted in the evolution of new strains. Although the immunosuppression caused by IBDV is more directed toward the B lymphocytes, the protective immunity in birds depends on inducement of both humeral and cell-mediated immune responses. Currently vaccination mainly used to control IBD. In this study, Group 1(n = 50) received the immune complex vaccine (Bursa-Plex®) s/c at 1 day of age. Group 2 (n = 50) received the GUMBORO (D78)(intervet)vaccine by drinking water and Group 3 (n = 50) were non IBD vaccinated birds. The aim of study: Evaluation between two types of IBD vaccines, immune-complex IBD vaccine (Bursaplex®) with the use of GUMBORO D78(intervet) vaccine. Depending on:At 7,14,21, 28th day P.V. • Serology (IBD ELISA (INFY)- cellular immunity).