Objective: To determine the frequency of pancytopenia among patients with vitamin B12 deficiency in a tertiary-care hospital, in Peshawar. Materials and Methods: A descriptive cross-sectional study was carried out at the Department of Hematology, Hayatabad Medical Complex, Peshawar from 18/4/2021 to 18/10/2021. In this study, a total of 252 patients were observed. From all patients, a sample of venous blood was obtained and sent to the hospital laboratory for the peripheral smear examination. Pancytopenia was diagnosed based on a peripheral smear showing Hemoglobin below 10g/dL, Total leukocyte counts less than 4,000 cells per mL, platelets count less than150,000 cells per mL, and reticulocyte count <2%. All the peripheral smears were done by an expert hematologist.  Strictly exclusion criteria were followed to avoid cofounders and make the study results clear of any bias. Results: In this study mean age was 42 years with a standard deviation of ± 15.84. Thirty-eight percent of patients were males and 62% of patients were females. Moreover, 5% of patients had pancytopenia and 95% of patients didn’t have pancytopenia. Conclusion:  The frequency of pancytopenia was 5% among the local patients with vitamin B12 deficiency. Keywords: pancytopenia, B12 deficiency, Peshawar, Pakistan.

The objective of our study was to assess the incidence of hepatitis B in volunteer donors at Regional Blood Center (RBC) Peshawar. The current study was prospective study carried out at the Regional Blood Center (RBC) Peshawar from 20/10/2022 31/12/2022. A complete clinical examination was carried out for all the volunteers. Under aseptic condition, 5ml blood sample was collected from all the enrolled individuals. The plasma was separated and was screened for HBsAg. Data analysis was done by using IBM SPSS. 23 version. In the current study, a total of 463 volunteer blood donors were included. The male volunteers were 460 (99.35%) whereas female volunteers were 3 (0.65%). The mean age (SD) in our study was 27.66 (4.63) years with maximum age of 55 years and minimum age of 18 years. The overall incidence of hepatitis B was 12 (2.59%). Our study concludes that hepatitis B is highly prevalent amongst volunteer blood donors.