Background: Physical activity has protective effects against the development of depression symptoms for all age groups. Cognitive training and aerobic training are lifestyle interventions that have been shown to have a positive impact on health, reducing cognitive impairment, and delaying the onset of dementia. Jump rope training is one type of aerobic training. Aerobic training is effective in improving mood. Objective: This study aims to prove the effect of jump rope training on adolescent’s mood as measured by the POMS score. Methods: This is an experimental study with 2 parallel groups pre-test and post-test design. The research subjects were 32 students of senior-high school 1 of Gunung Talang, Solok Regency, West Sumatra that were selected by purposive sampling and grouped into 2 groups. The control group without treatment (n=16), and the treatment group (n=16) were given jump rope training for 6 weeks. Mood scores were measured before and after the intervention using a profile of mood state (POMS) questionnaire and expressed as total mood disturbance (TMD) scores. Results: The research shown the significant decreases of TMD scores (p<0.001) on the treatment group rather than the control group. In addition, there was a significant difference between the post-test TMD scores of the control group and the treatment group (p=0.005). Conclusion: Jump rope training for 6 weeks can improve the mood of the adolescent.Keywords: aerobic training, jump rope training, mood, profile of mood state, total mood disturbance