This paper proposes a multi objective optimization of a power distribution system. The technique used here is network reconfiguration. The goal is to find an optimal configuration of the network which minimizes power losses while avoiding voltage drops and overloads online. To attain that goal, we minimize the active power losses and the voltage deviation at each node of the network. The minimization of the voltage deviation here consists in minimizing the reactive power losses online. The tool used is the GAMS software. The problem is solved by Mixed Integer Programming (MIP) which is a deterministic method. This method is implemented on two standard IEEE test power distribution networks 33-node and 69-node. The results obtained are satisfactory compared to other techniques in the literature.