ABS TRACT Pseudomyogenic hemangioendothelioma (PHE) is a rare neoplasm with vascular origin mostly seen on the extremities. Up to date, the terminology which represents PHE has been a subject to debate. According to the World Health Organization, PHE is classified among the soft tissue tumors. PHE is mostly seen in soft tissue planes and the distal lower extremities are the most affected location of the body. Localization of this tumor on the head and neck region is uncommon. PHE, being a sarcoma does not favor lymphogenic metastasis. As far as we are concerned, this is the first described case of PHE of the external ear and retro auricular sulcus. In this paper, the management of this case and the current treatment options of PHE are discussed.

Insulin-like growth factor-1 (IGF-1) and platelet rich plasma (PRP) on nerve healing to evaluate electrophysiologically and histopathologically by experimental traumatic peripheral facial paralysis in rats. Material and Methods: Three groups of 7 rats in each were formed. Group 1: Control group. Group 2: Local IGF-1 applied. Group 3: Local PRP applied. After nerve identification, neuron excitability threshold (NET), latency and amplitude values of left facial nerve buccal branch (LFNBB) were recorded. The LFNBB of all rats in all groups was cut and sutured. PRF was applied to Group 2, IGF-1 and Group 3, respectively. Control measurements of LFNBB were performed at 12 weeks. Then traumatized part of LFNBB was removed and axonal degeneration, vascular congestion and macrovacuolization were evaluated histopathologically. Results: When all groups were compared, significant difference was observed in Group 3 (p1=0.002, p2<0.001, p3=0.017 respectively) in NET. Group 2 and 3 values were significantly different than control group (p1=0.011, p2=0.007) in latency values. There was no difference between Group 2 and 3. Group 2 and 3 values were significantly different in amplitude values compared to control group (p1<0.001, p2<0.001). While there was no difference between Group 2 and 3. In all histopathological examinations, a significant improvement was observed in Group 2 and 3 compared to control group, findings of histopathological improvement in the Group 3 was superior. Conclusion: The findings obtained from this study showed that local IGF-1 and PRP application had positive effects on nerve healing in traumatic facial palsy while PRP was more effective.

Oral mukozal lezyonun morfolojik ozelliklerine gore yapılan ilk degȇrlendirme bize tanı ve takip acisından onemli bilgi vermektedir, bununla birlikte kesin tanı alınan biyopsi sonrasında yapılan histopatolojik inceleme sonucu konabilmektedir. Bu calısmada, oral mukozal lezyon nedeniyle biyopsi alınan hastaların histopatolojik tanıları degȇrlendirildi. Gereç ve Yontemler: 2009 ve 2016 yılları arasında oral mukozadan oral mukozal lezyon nedeniyle biyopsi alınan hastaların histopatoloji sonucļarı tanıların gorulme sıklıgȋna, lokalizasyonuna, yaş ve cinsiyet dagȋlımlarına gore degȇrlendirildi. Lezyonlar ayrıca benign nonneoplazik, benign neoplazik, premalign ve malign lezyon olma ozelliklerine gore gruplandırılarak her grup icin veriler incelendi. Bulgular: Uç yuz kırk hastanın 193'ü (%56,8) kadın, 147'si (%43,2) erkekti. Histopatolojik tanılar gruplara gore degȇrlendirildigȋnde 177 (%52,1) hastada benign nonneoplazik lezyon, 126 (%37,1) hastada benign neoplazik lezyon, 14 (%4,1) hastada premalign lezyon ve 23 (%6,8) hastada malign lezyon izlendi. Malign lezyonların buÿuk cogȗnlugȗnu skuamoz hucreli karsinom olusţurmaktaydı. Premalign ve malign lezyonlarda yaş ortalaması, benign lezyonlara sahip hastaların yaş ortalamasına gore anlamlı derecede yuksek bulundu (p<0,001). Sonuc: Oral mukozal lezyonların buÿuk cogȗnlugȗ benign karakterdedir. Yasin ilerlemesiyle premalign ve malign lezyonların gorulme sıklıgȋ artmakta, bununla birlikte genç hastalarda da premalign ve malign lezyonların gorulebilecegȋ akılda tutulmalıdır. Oral mukozal lezyonların takibinde en onemli noktalardan biri premalign ve malign lezyonların zamanında tanı konması ve tedavi uygulanmasıdır.Anah tar Ke li me ler: Ağız mukozası; biyopsi; patoloji; papillom; baş ve boyun skuamöz hücreli karsinomu ABS TRACT Objective:The first evaluation according to the morphological features of the oral mucosal lesion gives us important information in terms of diagnosis and follow-up, however, the accurate diagnosis can be made after histopathological examination. In this study, the histopathological diagnoses of patients who underwent biopsy for oral mucosal lesions were evaluated. Material and Methods: The histopathological results of patients who underwent oral mucosal biopsies between 2009 and 2016 were evaluated according to the frequency of occurrence, localization, age and gender distribution of the diagnoses. Lesions were also grouped according to their characteristics of being benign non-neoplastic, benign neoplastic, premalignant, and malignant, and data were analyzed within groups. Results: Of the 340 patients, 193 (56.8%) were female and 147 (43.2%) were male.When the histopathological diagnoses were evaluated according to the groups, 177 (52.1%) patients had benign non-neoplastic, 126 (37.1%) patients had benign neoplastic, 14 (4.1%) patients had premalignant, and 23 (6.8%) patients had malignant lesions. Most of the malignant lesions were squamous cell carcinoma. The mean age of premalignant and malignant lesions was found to be significantly highe...