Perforated Meckel's diverticulum (MD) in a preterm baby is very rare. We report a case of a very preterm baby, born at 29-week gestation, with a birth weight of 1400 g, admitted in the third hour of life to our intensive care unit (ICU) for respiratory distress syndrome with abdominal distention. An abdominal radiograph showed a pneumoperitoneum. Laparotomy revealed Meckel's perforation. The baby was discharged healthy at the age of 16 days. MD should be kept in mind as one cause of an acute abdomen in preterm neonates mimicking necrotizing enterocolitis. To our knowledge, our patient is the third reported case described in the literature and the first one revealed at birth.
Dermatofibrosarcoma protuberans (DFSP) is a low-to-intermediate grade sarcoma of dermal origin that rarely presents in the vulva, typically occurring on the trunk of young to middle-aged adults. Even though it has a low potential for distant metastases, it often recurs locally. Therefore, surgical excision is the treatment of choice. We report a case of DFSP with fibrosarcoma transformation involving the vulva treated by large excision with tumor free margins followed by plastic reconstruction. Our aim is to highlight this rare disease and through literature evaluate the safety and efficacy of surgical treatment. Early recognition of this rare entity whose localization and the aggressive nature of the fibrosarcomatous component will be an issue in the surgical management.
the histological type (p=0.036),tumor grade (p=0.009),depth of myometrial invasion(p=0.018),serous invasion(p=0.003),cervical invasion(p=0.013),lymphovascular space invasion (LVI) (<0.0001) and tumor necrosis (<0.0001).On multivariate analysis, independent factors of LN metastasis were, the presence of LVS (OR=0.312, 95%CI=0.012-0.533,p=0.041), tumor necrosis (OR=0.431,95%CI=0.111-0.668, p=0.041) and serous invasion(OR=0.264,95%CI=0.028-0.690, p=0.034) Conclusions Since LN metastasis represent an independent prognostic factor for survival, a nomogram based on histological and clinical characteristics could lead to a better detection of patients with high risk of LN metastasis
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