Objective: To assess the antibacterial goods of unrefined solvent methanol concentrate of Calligonum polygonoids, Asphadalous tenuiflous, Pulicaria crispa, and Fagonia cretica against a few human microorganisms. Method: Unrefined methanol concentrates of, Calligonum polygonoids, Asphadalous tenuiflous, Pulicaria crispa and Fagonia cretica at grouping of 500, 250 and 100µg/ml were considered in contrast to Gram-positive Staphylococcus carnosus and Gram -ve K. pneumoniae, S. typhi, E. coli and P. aurogenosa by utilizing circle dissemination strategy. Ciprofloxacin (5µg/ml) was utilized as a kind of perspective medication. Results: The concentrates of all plants showed expansive range antibacterial exercises in a portion subordinate way. The most noteworthy inhibitory area was seen from methanol concentrate of Fagonia cretica against Klebsiella pneumoniae (19mm), S. carnosus (19mm), E. coli (18.67mm) and S. typhi (14mm); Calligonum polygonoids showed against E. coli (15mm), S. typhi (16milimeter) and P. aurogenosa (16milimeter); Pulicaria crispa displayed against K. pneumoniae (19milimeter), E. coli (17milimeter) S. typhi (18milimeter), S. carnosus (19milileter) and P. aurogenosa (16milimeter) while Asphadalous tenuiflous displayed against K. pneumoniae (15milimeter), and E. coli (15milimeter) S. typhi (14.33milimeter), S. carnosus (13.67milimeter) and P. aurogenosa (13.67milimeter). Conclusion: These restorative plants have strong antibacterial action and might be the new hotspot for novel antibacterial compound disclosure for the treatment of medications safe human microorganisms.

The contemporary contagious ailment is caused by one of the deadliest coronaviruses, the SARS-COV-2. This novel zoonotic entity leads to multi-organ failure and an escalating threat and turbulence all over the world. Albeit a lot of work has been done to beat this virus, it is still radiating consistently. A colossal number of antiviral drugs has been tested to overcome the current pandemic but no promising remedy. A new approach to employ drug amalgamation such as remdesivir with hydroxychloroquine and losartan would better eradicate this outbreak. For this purpose, copper nanoparticles (extracted from a Prophetic, miraculous herb Nigella sativa) would serve as excellent transporters of such kinds of drug composites. In this review, the several possible therapies available across the world will be discussed in addition to the existing evidence for each of them. This new insight would be beneficial to fight against the latest rife.