INTRODUCTION: Gene expression levels are important for identifying and diagnosing diseases like cancer. Gene expression microarray information contains a high extent feature set, which minimizes the performance and the accuracy of classifiers. OBJECTIVES: This paper proposes a Modified Genetic Algorithm (MGA) that is based on Classifier Subset Evaluators -Genetic Search (Eval-CSE_GS) for selecting the relevant feature subsets. The MGA feature selection procedure is applied to microarray information for cancer patients that minimize a high dimension feature subset into low dimension feature subsets. METHODS: The various data mining methods for classifying the various kinds of cancer disease patients are presented. The proposed model refers to an ensemble model (PEM) for the organization of cancer disease by reducing the feature subsets, which results show improvements in the success rate. RESULTS: The proposed ensemble model obtains the accuracy of 94.58%, 96.56% and 97.04% for PEM-1 to PEM-3, respectively. CONCLUSION: Our proposed MGA-PEM model gives satisfactory results for cancer identification and classification.

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Atrial cardiopathy is a rare entity. It is a risk factor for persistent and undiagnosed atrial brillation. Atrial cardiopathy is known to cause many neurological illness. It can cause a stroke. Several studies have come up hypothesizing and highlighting the existence of atrial cardiopathy as an etiological cause of cryptogenic stroke. We reviewed the literature for the utility of direct oral anti-coagulants in prevention of stroke associated with atrial cardiopathy.

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Rhizopus arrhizus, a fungus of the Mucoraceae family, results in approximately 70% of cases of human mucormycosis and can cause various clinical syndromes including rhino-orbital-cerebral, cutaneous, gastric, and pulmonary disorders. [1] The diagnosis of mucormycosis is confirmed by the identification of the causative fungal organisms as broad nonseptate hyphae on cytology and isolation of R. arrhizus on cultures. The management of mucormycosis includes early aggressive surgical debridement along with the administration of liposomal amphotericin B. [2] Mucormycosis cases involving the central nervous system typically result from intracranial spread from fungal sinusitis or skull base osteomyelitis leading to cerebritis, meningitis, abscesses, or infarction secondary to vasculitis. [3,4] Mycotic intracranial aneurysms (MIAs) are extremely rare presentations of mucormycosis and most often result from local spread from skull base or cerebral infections. MIAs rarely may be caused from hematogenous seeding from extracranial Mucor infection. [5,6] case report A 57-year-old male patient presented with three episodes of tonic posturing of the right upper and lower limb lasting for 2-3 min followed by transient right hemiparesis for 15-20 min. The patient had a history of low-grade fever with fatigue of 3-week duration. Magnetic resonance imaging (MRI) brain and magnetic resonance (MR) angiography brain and neck vessels following each episode were unremarkable. Electroencephalography, echocardiography, Doppler study of the neck vessels, and cerebrospinal fluid (CSF) examination were normal. Hematological and metabolic parameters were within normal limits except for elevated serum creatinine (2.1 mg/dl) and HbA1c (7.8.). The patient had an 8-year history of diabetes and hypertension with coronary artery disease. The patient had chronic kidney disease IV with a