Background and Objective: Human beings are under threat from many chronic diseases and life style disorders. A major cause of all these diseases was found to be improper lifestyle and stress leading to obesity and excessive lipid peroxidation, indicating increased production of reactive oxygen species. Yoga therapy concentrates on purification of body and mind through its integrated holistic approach one can overcome the different kinds of afflictions in life. Hence the present study was undertaken to find out the effect of intervention of yoga therapy in obese individuals. Materials and Methods: The study was conducted at MRPL ladies club auditorium in the MRPL Township after an informed and written consent from all the participants. The research protocol was approved by institutional ethics committee. The study consisted of forty obese male and female subjects. The changes in Body weight, Body Mass Index, Blood sugar, MDA level and Total antioxidant status was estimated before and after one month of yoga therapy. The data obtained was analyzed using paired't' test.p<0.05 was the level of significance. Result: There was a significant decline in the Body Weight (p=0.020), BMI (p=0.000), Fasting Blood Sugar (p=0.03) and Post Prandial Blood Sugar (p=0.000) MDA (p=0.000) and significant increase in Total Antioxidant Level (p=0.021) after yoga when compared to that before the yoga therapy. Conclusion: Yoga therapy is beneficial in maintaining better health by regulating BMI, Oxidative status by improving the biochemical functions of the body and helpful to overcome the complications of obesity.

Background: Clear cell carcinoma of the ovary (CCCO) shows unique clinical features. There is a remarkable difference in incidence among different ethnic  populations. The reasons for these differences in incidence around the world are not known. Aim and objectives: To evaluate the clinical characteristics of patients with CCCO and to determine the impact of the stage of the disease and the extent of surgery on the prognosis of those patients. Materials and methods: A retrospective analysis of the cases of clear cell carcinoma of the ovary that were operated in the regional cancer centre, Cuttack, from January 2009 to December 2018, was performed to evaluate the clinical characteristics and prognostic factors of the patients.  Results: During this study period, the incidence of CCCO was found to be 1.92%. The most common age group was 40–50 years (mean age of 44.7 years). The most common modes of presentation were abdominal distention and pain in the abdomen. Most of the cases in this study belonged to stage III C (65%), making it the most common stage in this group. 20% of the patients within the study group were nulliparous and 35% were menopausal in status.40% of the tumours were >15 cm in size. Almost 28% were lymph node positive. None in stage I had positive lymph nodes. All the cases in stage III were positive for lymph nodes. So, in stage III, 38.5% were positive for lymph nodes. 17/20 had some form of chemotherapy, of which 45% had NACT. Survival curves differ significantly between the early and advanced stages of the disease. A trend of survival benefit is seen with complete cytoreduction. Conclusion: There is a need for data regarding the incidence and specific clinicopathologic behaviour of clear cell carcinoma of the ovary in the Indian population. This is an attempt to compile the data from a single tertiary institute in eastern India over the past 10 years. This is a rare tumour and the chances of missing data are well accepted. The survival advantage of early-stage-diagnosed patients over late-stage patients is tremendous and hard to ignore. Combining the fact that clear cell carcinomas are associated with precancerous lesions like atypical endometriosis and atypical adenofibroma, there may be scope for screening. The mutational changes leading to malignancy in these precancerous lesions also need to be refined. As stated, complete cytoreduction is the key to survival advantage and the need for referral to a centre with proper expertise for the same needs to be emphasized.