Bachground & Aims: Oral lichenoid reactions (OLR) and oral lichen planus (OLP) are clinically and histopathologically similar but their therapeutic approach are different. Due to the presence of dysplasia in oral lichen planus which effects prognosis, the aim of study was the evaluation of proliferation activity of OLPs and OLRs and their subtypes. AgNOR technique that is inexpensive and easy to perform was used to differentiate OLPs and OLRs and their subtypes. Result: There were significant differences between OLP(and its subtypes) and N and also between OLR(and erosive type) and N .Such a difference was also between reticular OLP and reticular OLR.with regard to AgNOR count.
Conclusion:Since reticular OLP had significantly higher AgNOR count than reticular OLR in our study, we can suggest the use of AgNOR technique for differentiation of reticular type of OLP from OLR on challenging histopathologic cases.
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